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The US Supreme Court ruled against Microsoft (NASDAQ:MSFT) today, rejecting its appeal of a $290 million jury verdict for infringing on a patent held by Canadian software firm i4i, Bloomberg reported.The Court unanimously upheld the US Appeals Court ruling, rejecting Microsoft's argument to adopt a lower standard to replace the long-standing requirement that a defendant in a patent infringement case prove "by clear and convincing evidence" that a plaintiff's claim is invalid.Microsoft argued lowering the standard of proof involving a "preponderance of the evidence" would make some patents more vulnerable to legal challenge while promoting innovation and competition.I4i, supported by the Obama administration, argued that such a radical change in patent law should come from Congress, which has been considering patent legislation.Microsoft has a potential upside of 38.2% based on a current price of $23.92 and an average consensus analyst price target of $33.05.